Yes and no. Because IRIS Clarity is a desktop app, as long as one caller is speaking from a computer which has IRIS Clarity installed, then voices will be isolated on both sides of the call, mobile devices included. If both callers are on mobile, then no, IRIS Clarity does not yet work as a mobile app.
Example: You're calling a client from your laptop and reach them on their mobile phone. They can't have IRIS Clarity on their phone, but you have it installed on your computer. Because IRIS Clarity is multi-directional, the background noise from both your end of the call and your client's end of the call will be removed — even if they're on mobile.